
OPALESCE is a range of top-quality cosmeceuticals to provide clients with a homecare regime equating to clinical treatments.


OPALESCE is a range of top-quality cosmeceuticals to provide clients with a homecare regime equating to clinical treatments.
The opalesce range
OPALESCE Cosmeceuticals have a higher concentration of active ingredients than cosmetic skin care products to have a better, effective anti-ageing and anti-pigmentation result as well as improving the skin’s complexion and health. All the products in the range are free from Petrochemicals, PEGs, SLS, Ethoxylates, Formaldehyde donors, Artificial colourants, Artificial fragrance and Parabens. All the packaging is recyclable.
Skin lightening capsules
Product Info
Premium skin lightening capsules contain powerful natural ingredients that have been shown to have significant positive effects on skin tone and appearance, including reducing dark marks and melasma.
Continue scrolling down on our website for more information on the benefits and results of this breakthrough product.
Intense Night Repair Cream
Product Info
A powerful nourishing cream enriched with crucial barrier repair actives, powerful antioxidants and deep moisturising properties. Suitable for all skin types. This cream could double as a day cream for those suffering from dry skin.
Hydrating Day Repair Cream
Product Info
A day cream that offers all day hydration while still protecting precious barrier skin function. We have designed our Hydrating Day Repair Cream to create a velvety soft feel to the touch with deep hydration to keep it that way all day. Suitable for all skin types.
SPF50 Facial Sunblock
Product Info
Hydrolyzed Collagen
Product Info
Glyco-Lactic Cleanser
Product Info
SLS free & perfect for all skin types. This cleanser boasts incredible exfoliating properties & is ideal for those wishing to improve the texture & appearance of their skin without altering their skin pH. An added benefit is that this chemical exfoliation will strengthen the skin while increasing collagen and elastin production.
Hydrating Serum
Product Info
A serum containing multi molecular hyaluronic acid designed to penetrate to different layers of the skin. Hyaluronic acid attracts and holds moisture offering advanced hydration benefits.
Rejuvenation Eye Cream
Product Info
A luxurious, smooth, silky, eye treatment for wrinkles, dark circles and puffiness. Absorbs readily with no greasy after feel.
Clinical Antioxidant Serum
Product Info
A powerful antioxidant serum that scavenges free radicals and provides defense against environmental assault due to pollutants and contaminants. Modern living exposes us to smoke, industrial gases and other substances that cause oxidative damage to our skin. This chain reaction can be halted by proliferating the skin with antioxidants.
Opalesce Skin Lightening Capsules
Pinnacle Offering in Our Lineup
Welcome to the complexion and skin tone you’ve always wanted
OPALESCE premium skin lightening capsules contain powerful natural ingredients that have been shown to have significant positive effects on skin tone and appearance, including reducing dark marks and melasma.
OPALESCE is a 100% natural, non-toxic product containing no GMO or animal-derived ingredients. It is considered safe for all patients and can transform how you see yourself – and how others see you.
OPALESCE is easy to take and is available from dermatologists, spas and beauty clinics without the need for a consultation or prescription.
OPALESCE is suitable for patients of all skin tones. It works as a natural sunscreen and melanin inhibitor, and can help prevent DNA damage.
Dark Spots
Treats dark spots on the skin.
Sun Protection
Provides enhanced sun protection.
Melasma
Treats and prevents Melasma.
Skin Beauty from within
In contrast to topical preparations, OPALESCE skin lightening capsules provide all-over skin health and beauty benefits.
By providing enhanced sun protection, it can prevent the development of melasma and other skin-darkening conditions.
Safe
Effective
Natural
No GMO
Before & After

Join the Revolution
Because OPALESCE is a revolutionary new product range, we understand that you may have questions before you use it. We’re happy to provide any information you may need – please click our FAQ link for answers to the most common questions that patients have asked.
If after reading through the FAQ section, you’d still like more information, please feel free to contact us.
Introducing our new complementary cleanser
Opalesce Creamy Glyco-Lactic Cleanser
The OPALESCE Creamy Glyco-Lactic Cleanser is formulated to stimulate cellular renewal and reveal smoother revitalised skin and a good complimentary product to our OPALESCE Skin Lightening Capsules.
OPALESCE Creamy Glyco-Lactic Cleanser is SLS free & perfect for all skin types. This cleanser boasts incredible exfoliating properties & is ideal for those wishing to improve the texture & appearance of their skin without altering their skin pH.
An added benefit is that this chemical exfoliation will strengthen the skin while increasing collagen and elastin production.
For Physicians
Why OPALECSE Skin Lightening Capsules?
A premium approach to skin lightening – without prescription
As a physician treating skin complaints, you can recommend OPALESCE with confidence to patients who are looking for a lighter, brighter skin tone, to correct skin blemishes, or to prevent future skin damage.
OPALESCE contains the colourless carotenoids phytoene and phytofluene to enhance and augment the skin’s natural beauty from within.
Combats free radicals
OPALESCE also contains L-cysteine, the amino acid precursor to the antioxidant glutathione (GSH). Unlike the synthetic glutathione found in many skin lightening products, L-cysteine is readily absorbed by the gut and results in significantly higher levels of in vivo glutathione.
In addition to its antioxidant properties, glutathione lightens melanin by deactivating the enzyme tyrosinase, thereby reducing the pigment.
Sun Protection
After taking OPALESCE carotenoids, 65% of the volunteers had their natural skin SPF increased by 20% after 12 weeks. (Khachik F, et al. Pure & Appl. Chem., 63, 71-80, 2002).
Skin was also improved in term of roughness, suppleness, texture and tone evenness in 90 to 100% of the subjects. (Khachik, F. et al. Exp Biol Med 227, 845-851, 2002).
Proven effectiveness
Multiple studies have shown the effectiveness of OPALESCE and its active ingredients:
Reduction in existing melanin
Data shows that the carotenoids in OPALESCE reduce the existing melanin in melanoma cell culture by a very significant amount.
Skin repair and protection
Studies have demonstrated that these colourless carotenoids have powerful photoprotective and skin lightening effects.
They can make the skin visually healthier and more resistant to future sun and oxidative damage.

Additional Research
Fuller B.B., et al. J. Cos. Der.,
2006 March. 5(1):30
Khachik, F. et al. Exp BiolMed.,
227, 845-851, 2002
KhachikF, et al. Pure & Appl. Chem.,
63, 71-80, 2002
Presentation
Click on the link below to download a detailed PDF presentation outlining the mechanism and benefits of OPALESCE.
Skin Lightening Capsules
Frequently Asked Questions
Why ‘OPALESCE’?
OPALESCE means to be bright or brilliant; to shimmer, sparkle or glow, and to be resplendent, dazzling and radiant. That’s exactly the effect this premium skin lightening product can have on your skin!
What are the active ingredients of OPALESCE?
OPALESCE is a 100% natural, GMO-free and vegan-friendly product containing potent colourless carotenoids and L-cysteine, a natural precursor to glutathione. The daily amounts (total for the three daily capsules) are:
- Colourless carotenoids – 840mg
- L-cysteine – 510mg (over ten times the amount found in some other skin lightening capsules)
How does OPALESCE work?
Colourless carotenoids – derived from hybrid white tomatoes – provide multiple skin health and beauty benefits:
- Provide protection against skin damage caused by the sun (including melasma) and environmental factors;
- Can encourage a lighter, more even skin tone;
- Promote a more youthful complexion;
- Inhibit the synthesis of melanin (which causes darker skin tone and melasma);
- Help to naturally control skin pigmentation and darkening; and
- Can reduce inflammation and skin damage.
Colourless carotenoids have been shown to make the skin more radiant, better hydrated and more supple, with a more even tone.
L-cysteine is an amino acid that helps your body to produce glutathione, a very powerful antioxidant. L-cysteine is easily absorbed by your gut, meaning that much more glutathione becomes available for your body to use. This is important because glutathione:
- Can combat dangerous free radicals;
- Helps to boost your immune system;
- Helps to purge toxins from your body; and
- Can promote skin lightening.
Is OPALESCE effective against melasma?
Who should take OPALESCE?
OPALESCE is designed to help you achieve a brighter, lighter complexion and to correct skin blemishes. It is an ideal treatment for melasma and can help reverse sun damage, while providing protection against further damage.
How long should I take OPALESCE for?
This will vary from patient to patient. Many patients see results within 1 – 2 months. Stopping taking OPALESCE can cause skin blemishes to gradually return, so long-term use for skin tone maintenance is recommended.
What form does OPALESCE come in?
OPALESCE is sold in bottles of 90 capsules. The recommended dose is three capsules per day, taken orally. Each bottle therefore provides 30 days’ supply of OPALESCE skin lightening capsules.
How much does OPALESCE cost?
The recommended retail price for OPALESCE is R1 800.00 per 90-capsule bottle. This equates to just R60.00 per day.
Why is OPALESCE more expensive than some other products?
Cheaper skin lightening products are available, but many of these contain synthetic glutathione which cannot be absorbed by your gut. This means that it never becomes bioavailable and is ultimately flushed from your body as a waste product. In other words, skin lightening products based on synthetic glutathione are ineffective and a waste of money, even if they appear to offer better value.
Where can I buy OPALESCE?
OPALESCE is available from leading dermatologists, spas and beauty therapists. Alternatively, click here to purchase OPALESCE online.
Do I need a prescription?
OPALESCE is classed as a ‘dietary supplement’ so no prescription is required.
Has OPALESCE been approved by the Medicines Council of SA?
As OPALESCE is classed as a ‘dietary supplement’, no approval is required. However, colourless carotenoids have been classified as GRAS (Generally Recognized As Safe) by the US FDA, the European Food Safety Authorities and other regulatory agencies.
In addition, the EU Scientific Committee for Food has concluded that L-cysteine is safe as a food additive.
Are there any side-effects?
OPALESCE has no known side-effects. During clinical trials, colourless carotenoids did not demonstrate any side-effects. Taking extra capsules would have the same effect as eating an extra tomato. OPALESCE has been tested in multiple clinical trials and has been shown to be effective and safe.
Will taking OPALESCE change the colour of my skin?
Because OPALESCE contains colourless carotenoids, it does not affect the colour of your skin. Alternative products that contain red or orange carotenoids can cause your skin to take on an orange hue.
Where is OPALESCE manufactured?
The powder content of OPALESCE capsules is manufactured in licensed factories in Europe, and then placed in capsules here in South Africa.
Ingredients
Natural Extracts
The potent natural extracts in OPALESCE include colourless carotenoids and L-Cysteine for proven skin health and beauty benefits thanks to their powerful antioxidant properties.
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Stockists
Skin Lightening Capsules are available from these fine clinics
Johannesburg
Dr Alastair Clark, Sandton Aesthetic Institute
127 10th Street, Parkmore, Johannesburg
Phone: 011 883 3116
Dr Lushen Pillay, Skinderm
Suites 303-304, Third Floor, 200 Rivonia Road, Morningside
Sandton
Phone: 011 304 7772
Dr Reza Mia, Anti-Aging Art
St. James, 52 Central Street,
Houghton, Johannesburg
Phone: 011 483 0881
Natural Expressions
114 11th Ave, Parkmore, Johannesburg
Phone: 011 783 0270
Skinstitute
5c Stirling Avenue, Buccleuch, Sandton
Phone: 071 149 6112
Krugersdorp
Dr LBA Monaisa, Marang Aesthetics
NetCare Pinehaven, Ground floor suite 009
1 Gateway road Pinehaven Estates
Krugersdorp 1739
Phone: 011 950 5512
Pretoria
Dr Genevieve Marks, Dermatology
277 Delphinus Street, cnr Rigel Ave & Delphinus Street
Waterkloof Ridge Pretoria
Phone: 012 460 7047/67
Dr Sujata Garach, Aesthetic and Women Wellness
Suite 2 Savannah Centre
290 Tangerine Street Laudium
Phone: 012 374 0324
Dr Raeesa Joosub
Ground Floor Eldomed Centre,
1286 Willem Botha Drive,
Centurion
Phone: 012 660 0111
Durban
Durban Cosmetic Laser Centre Morningside
461 Innes Rd, Morningside, Durban
Phone: 031 312 3934
Zimbabwe
Dr Vivek Solanki
Aesthetic Clinic and Jet Fuel Drip Bar
Trauma Centre Borrowdale, Harare
Phone: +263 78 383 6686
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